Quick notes – MEN syndromes

MEN Syndromes

MEN 1 – Autosomal dominant, affected gene: menin

Pancreatic tumours (only in MEN-1)

Pituitary adenomas

Parathyroid hyperplasia

MEN 2

2a:       Parathyroid hyperplasia

            Medullary thyroid ca (raised calcitonin)

            Phaeochromocytoma (only in MEN-2A)

2b:       Medullary thyroid ca

            Marfanoid body habitus

            Mucosal neuromata