Coeliac Disease Coeliac disease :– chronic inflammation triggered by ingestion of gluten– results in dense infiltrationof lymphocytes in the proximal small bowel– Histology findings: mucosal inflammation, crypt hyperplasia, villous atrophy Endoscopically visible hallmarks:– Scalloped duodenal folds– Gorooves and fissurations– As opposed to normal finger like villi, in coeliac the villi are much shorter and less pronounced Figure 1: normal, finger like villi Figure 2: Flattened villi Figure 3: nodular appearance with fissures, indicates absence of villi Figure 4: granular appearance, fissures visible. Treatment Life-long adherence to a gluten free diet (including those that may have had contact with gluten. (eg. wheat, barley, bulgur, semolina) Also avoid toasters, air fryers where gluten would be hard to clea